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Mixed connective tissue disease

Mixed connective tissue disease

For mixed connective tissue disease characterized by a combination of symptoms of scleroderma, rheumatoid arthritis, polymyositis and systemic lupus erythematosus (SLE). Defeat in mixed connective tissue disease characterized by kidney for children, adults are rare.

Antibodies to RNP-70

Circulating antibodies to RNP-70 are a specific marker for mixed connective tissue disease, while antibodies to other extractable nuclear antigens and DNA are missing or are found in low titre.