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Systemic scleroderma

Systemic scleroderma

Systemic scleroderma — is an autoimmune connective tissue disease, the main clinical features are due to a common disorder of microcirculation, fibrosis of the skin and internal organs.

Antibodies to the centromere B and topoisomerase I (Scl-70)

In systemic sclerosis have a value of antibodies against centromere B and topoisomerase I (Scl-70) as diagnostic indicators of limited and diffuse systemic sclerosis, respectively.