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Americaine

Americaine - General Information

A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

 

Pharmacology of Americaine

Americaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula.

 

Americaine for patients

Patient should discontinue Benzocaine if irritation, or skin rash occurs. Do not use in infants under 1 year of age.

 

Americaine Interactions

No information is available.

 

Americaine Contraindications

Known allergy or hypersensitivity to benzocaine.

 

Additional information about Americaine

Americaine Indication: For general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex.
Mechanism Of Action: Americaine binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Benzocaine
Synonyms: Ethyl Aminobenzoate; Ethylester Kyseliny P-Aminobenzoove; Ethyl P-Aminophenylcarboxylate; Ethyl P-Aminobenzoate; P-Aminobenzoic Acid, Ethyl Ester; P-Carbethoxyaniline; P-Ethoxycarboxylic Aniline
Drug Category: Anesthetics; Antipruritics; Local Anesthetics
Drug Type: Small Molecule; Approved
Other Brand Names containing Benzocaine: Aethoform; Amben Ethyl Ester; Americaine; Anaesthan-Syngala; Anaesthesin; Anaesthin; Anestezin; Anesthesin; Anesthesine; Anesthone; Baby Anbesol; Dermoplast; Ethoform; Hurricaine; Identhesin; Keloform; Norcain; Norcaine; Ora-Jel; Orthesin; Parathesin; Parathesine; Solu H; Topcaine;
Absorption: Not Available
Toxicity (Overdose): LD50=3040 mg/kg (rat, oral)
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Americaine: Liquid Topical
Gel Topical
Paste Dental
Ointment Topical
Swab Topical
Gel Dental
Aerosol Buccal
Swab Oral
Liquid Oral
Paste Oral
Aerosol Dental
Gel Oral
Chemical IUPAC Name: ethyl 4-aminobenzoate
Chemical Formula: C9H11NO2
Benzocaine on Wikipedia: http://en.wikipedia.org/wiki/Benzocaine
Organisms Affected: Humans and other mammals