Apo-Bromazepam - General Information
One of the benzodiazepines that is used in the treatment of anxiety disorders. [PubChem] It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances.
Pharmacology of Apo-Bromazepam
Apo-Bromazepam is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal muscle relaxant properties. It does not possess any antidepressant qualities. Apo-Bromazepam shares with other benzodiazepines the risk of abuse, misuse, psychological and/or physical dependence. According to many psychiatric experts Apo-Bromazepam has a greater abuse potential than other benzodiazepines because of fast resorption and rapid onset of action.
Additional information about Apo-Bromazepam
Apo-Bromazepam Indication: For the short-term treatment of insomnia, short-term treatment of anxiety or panic attacks, if a benzodiazepine is required, and the alleviation of the symptoms of alcohol- and opiate-withdrawal.
Mechanism Of Action: Apo-Bromazepam binds to the GABA receptor GABAA, causing a conformational change and increasing inhibitory effects of GABA. Other neurotransmitters are not influenced.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Bromazepam
Synonyms: 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one; 7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiazepin-2(1H)-one; Bromazepamum [inn-latin]
Drug Category: Benzodiazepines; Hypnotics and Sedatives
Drug Type: Small Molecule; Illicit; Approved
Other Brand Names containing Bromazepam: Apo-Bromazepam; Calmepam; Compedium; Compendium; Creosedin; Durazanil; Gen-Bromazepam; Lectopam; Lekotam; Lexaurin; Lexilium; Lexomil; Lexotan; Lexotanil; Normoc; Novo-bromazepam; Nu-Bromazepam; Ultramidol; Somalium;
Absorption: Bioavailability is 84% following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatically, via oxidative pathways (via an enzyme belonging to the Cytochrome P450 family of enzymes).
Half Life: 10-20 hours
Dosage Forms of Apo-Bromazepam: Tablet Oral
Chemical IUPAC Name: 7-bromo-5-pyridin-2-yl-1,3-dihydro-1,4-benzodiazepin-2-one
Chemical Formula: C14H10BrN3O
Bromazepam on Wikipedia: http://en.wikipedia.org/wiki/Bromazepam
Organisms Affected: Humans and other mammals