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Apo-Tenoxicam

Apo-Tenoxicam - General Information

Apo-Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

 

Pharmacology of Apo-Tenoxicam

Apo-Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.

 

Additional information about Apo-Tenoxicam

Apo-Tenoxicam Indication: For the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.
Mechanism Of Action: The antiinflammatory effects of tenoxicam may result from the inhibition of the enzyme cycooxygenase and the subsequent peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, their inhibition accounts for the peripheral analgesic effects of tenoxicam. Antipyresis may occur by central action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat loss.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Tenoxicam
Synonyms: Not Available
Drug Category: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors
Drug Type: Small Molecule; Approved
Other Brand Names containing Tenoxicam: Apo-Tenoxicam; Novo-Tenoxicam; Tenoxicam [Usan-Ban-Inn-Jan]; Tenoxicamum [Inn-Latin]; Tilcotil;
Absorption: Oral absorption of tenoxicam is rapid and complete (absolute bioavailability 100%).
Toxicity (Overdose): Not Available
Protein Binding: 99%
Biotransformation: Tenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam).
Half Life: 72 hours (range 59 to 74 hours)
Dosage Forms of Apo-Tenoxicam: Tablet Oral
Chemical IUPAC Name: (3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one
Chemical Formula: C13H11N3O4S2
Tenoxicam on Wikipedia: Not Available
Organisms Affected: Humans and other mammals