Argicillin - General Information
A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect.
Pharmacology of Argicillin
Argicillin is an anticholinergic drug, a medication that reduces the effect of acetylcholine, a chemical released from nerves that stimulates muscles, by blocking the receptors for acetylcholine on smooth muscle (a type of muscle). It also has a direct relaxing effect on smooth muscle. Argicillin is used to treat or prevent spasm in the muscles of the gastrointestinal tract in the irritable bowel syndrome. In addition, Argicillin inhibits gastrointestinal propulsive motility and decreases gastric acid secretion and controls excessive pharyngeal, tracheal and bronchial secretions.
Additional information about Argicillin
Argicillin Indication: For the treatment of visceral spasms
Mechanism Of Action: Action is achieved via a dual mechanism: (1) a specific anticholinergic effect (antimuscarinic) at the acetylcholine-receptor sites and (2) a direct effect upon smooth muscle (musculotropic).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Oxyphenonium
Synonyms: Methocidin [Dcf:Inn]; Methocidine [Inn-French]; Methocidinum [Inn-Latin]; Metocidina [Inn-Spanish]; Oxyphenonium Bromide; Hydroxymethylgramicidin; DCF; Oxiphenonum
Drug Category: Mydriatics; Muscarinic Antagonists; Parasympatholytics
Drug Type: Small Molecule; Approved
Other Brand Names containing Oxyphenonium: Antrenyl; Argicillin; Methacin; Methocidin;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: 93% bound to albumin
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Argicillin: Not Available
Chemical IUPAC Name: 2-(2-cyclohexyl-2-hydroxy-2-phenylacetyl)oxyethyl-diethyl-methylazanium
Chemical Formula: C21H34NO3+
Oxyphenonium on Wikipedia: Not Available
Organisms Affected: Humans and other mammals