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Squamous cell carcinoma antigen (SCC)

Squamous cell carcinoma antigen (SCC)

The indications for squamous cell carcinoma antigen (SCC) - monitoring course and therapy of squamous cell carcinoma of the cervix, nasopharynx, ear, lungs and esophagus. Squamous cell carcinoma antigen is a glycoprotein with a molecular weight of 42 kDa, isolated from liver metastases of squamous cell carcinoma of the cervix.

Limit of normal antigen squamous cell carcinomais not higher than 2 ng/ml.

Elevated levels of squamous cell carcinoma antigenis diagnosed in patients with squamous cell carcinoma of the cervix (85%), in carcinoma of the nasopharynx and ear (60%). Increased levels of squamous cell carcinoma antigen are found in renal failure (up to 10 ng/ml), sometimes patients with hepatobiliary pathology.

In the study of this marker you should pay attention to the material and work with the test samples, as contamination by elements of the skin and saliva leads to false-positive results.

Elevated levels of squamous cell carcinoma antigen detected in 31% of cases of squamous cell lung carcinoma, and in 17% of cases of lung cancer.