Roger’s sign, or the numb chin syndrome, is an isolated neuropathy affecting the mental branch of the mandibular division of the trigeminal (V) nerve, causing pain, swelling, and numbness of the lower lip, chin and mucous membrane inside the lip. This is usually a sign of metastatic spread of cancer to the jaw.
Hypoesthesia involving the cheek, upper lip, upper incisors and gingiva, due to involvement of the infraorbital portion of the maxillary division of the trigeminal nerve ("numb cheek syndrome") is also often an ominous sign, resulting from recurrence of squamous cell carcinoma of the face infiltrating the nerve.
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Roger H, Paillas J. Le signe du mentonnier (parasthésie et anesthésie unilatérale) révélateur d’un processus néoplasique métastatique. RevueNeurologique (Paris) 1937; 2: 751-752