Amcoral - General Information

Amcoral (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.


Pharmacology of Amcoral

Amcoral is a positive inotropic cardiotonic with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.


Additional information about Amcoral

Amcoral Indication: Used in the treatment of congestive heart failure.
Mechanism Of Action: Amcoral is a phosphodiesterase inhibitor, resulting in increased cAMP and therefore an increase in the calcium influx like that caused by beta-agonists resulting in increased inotropic effect.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Amrinone
Synonyms: Inamrinone; Amrinona [inn-spanish]; Amrinonum [inn-latin]; Inamrinone lactate
Drug Category: Calcium Channel Blockers; Cardiotonic Agents; Phosphodiesterase Inhibitors; Vasodilator Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Amrinone: Inocor; Amcoral; Cartonic; Cordarex; Cordemcura; Wincoram;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: 10 to 49%
Biotransformation: Hepatic.
Half Life: 5 to 8 hours
Dosage Forms of Amcoral: Liquid Intravenous bolus
Liquid Intravenous drip
Chemical IUPAC Name: 3-amino-5-pyridin-4-yl-1H-pyridin-2-one
Chemical Formula: C10H9N3O
Amrinone on Wikipedia:
Organisms Affected: Humans and other mammals