Clozan - General Information

Clozan is a benzodiazepine derivative, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.


Pharmacology of Clozan

Clozan is a benzodiazepine derivative possessing anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Stage 2 NREM sleep is significantly increased by clotiazepam.


Additional information about Clozan

Clozan Indication: For the treatment of anxiety disorders.
Mechanism Of Action: Clozan acts at the benzodiazepine receptors (BZD). This agonizes the action of GABA, increasing the frequency of opening of the channel chlorinates and penetration of the ions chlorinates through the ionophore. Increase in membrane polarization decreases the probability of discharge of neurons.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Clotiazepam
Synonyms: Clotiazepamum [inn-latin]
Drug Category: Benzodiazepines; Anti-anxiety Agents; Hypnotics and Sedatives; Anticonvulsants
Drug Type: Small Molecule; Illicit; Approved

Other Brand Names containing Clotiazepam: Rize; Rizen; Tienor; Trecalmo; Veratran; Distensan; Clozan;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: 99% bound to plasma proteins.
Biotransformation: Hepatic.
Half Life: 4 hours
Dosage Forms of Clozan: Tablet Oral
Chemical IUPAC Name: 5-(2-chlorophenyl)-7-ethyl-1-methyl-3H-thieno[3,2-f][1,4]diazepin-2-one
Chemical Formula: C16H15ClN2OS
Clotiazepam on Wikipedia:
Organisms Affected: Humans and other mammals