Creatin - General Information

An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatin is excreted as creatinine in the urine. [PubChem]


Pharmacology of Creatin

Creatin is a essential, non-proteinaceous amino acid found in all animals and, in some plants. Creatin is synthesized in the kidney, liver and pancreas from L-arginine, glycine and L-methionine. Following its biosynthesis, creatine is transported to the skeletal muscle, heart, brain and other tissues. Most of the creatine is metabolized in these tissues to phosphocreatine (creatine phosphate). Phosphocreatine is a major energy storage form in the body. Supplemental creatine may have an energy-generating action during anaerobic exercise and may also have neuroprotective and cardioprotective actions.


Additional information about Creatin

Creatin Indication: For nutritional supplementation, also for treating dietary shortage or imbalance
Mechanism Of Action: In the muscles, a fraction of the total creatine binds to phosphate - forming creatine phosphate. The reaction is catalysed by creatine kinase, and the result is phosphocreatine (PCr). Phosphocreatine binds with adenosine diphosphate to convert it back to ATP (adenosine triphosphate), an important cellular energy source.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Creatine
Synonyms: (alpha-Methylguanido)acetic acid; Creatine, hydrate; N-Methyl-N-guanylglycine; N-Amidinosarcosine; Methylguanidoacetic acid; Creatine (8CI)
Drug Category: Dietary supplement; Micronutrient
Drug Type: Small Molecule; Nutraceutical; Approved

Other Brand Names containing Creatine: Cosmocair C 100; Creatin; Kreatin; Krebiozon; Phosphagen; Pyrolysate;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Creatin: Not Available
Chemical IUPAC Name: 2-(carbamimidoyl-methylamino)acetic acid
Chemical Formula: C4H9N3O2
Creatine on Wikipedia:
Organisms Affected: Humans and other mammals