Doriden - General Information
A hypnotic and sedative. Its use has been largely superseded by other drugs. [PubChem]
Pharmacology of Doriden
Doriden is a hypnotic sedative that was introduced in 1954 as a safe alternative to barbiturates to treat insomnia. Before long, however, it had become clear that glutethimide was just as likely to cause addiction and caused similarly severe withdrawal symptoms.
Additional information about Doriden
Doriden Indication: For the treatment of insomnia.
Mechanism Of Action: Not Available
Drug Interactions: Anisindione The agent decreases the anticoagulant effect
Dicumarol The agent decreases the anticoagulant effect
Acenocoumarol The agent decreases the anticoagulant effect
Warfarin The agent decreases the anticoagulant effect
Donepezil Possible antagonism of action
Galantamine Possible antagonism of action
Rivastigmine Possible antagonism of action
Food Interactions: Take without regard to meals.
Generic Name: Glutethimide
Synonyms: Gluthetimide; Glutathimid; Glutethimid; Glutetimid; Glutetimide
Drug Category: Hypnotics and Sedatives
Drug Type: Small Molecule; Illicit; Approved
Other Brand Names containing Glutethimide: Sarodormin; Doriden; Elrodorm; Alfimid; Noxiron; Noxyron; Ondasil; Rigenox; Glimid; Gimid;
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic. Glutethimide is almost completely metabolized.
Half Life: 10-12 hours
Dosage Forms of Doriden: Not Available
Chemical IUPAC Name: 3-ethyl-3-phenylpiperidine-2,6-dione
Chemical Formula: C13H15NO2
Glutethimide on Wikipedia: https://en.wikipedia.org/wiki/Glutethimide
Organisms Affected: Humans and other mammals