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Dormalin

Dormalin - General Information

Dormalin is a drug which is a benzodiazepine derivative. It induces impairment of motor function and has hypnotic properties. Dormalin is used to treat insomnia.

 

Pharmacology of Dormalin

Dormalin is a benzodiazepine derivative. The main pharmacological action of quazepam is the enhancement of the neurotransmitter, GABA at the GABAA receptor.

 

Additional information about Dormalin

Dormalin Indication: Used to treat insomnia.
Mechanism Of Action: Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Quazepam
Synonyms: Quazepamum [inn-latin]
Drug Category: Anti-anxiety Agents; Benzodiazepines; GABA Modulators
Drug Type: Small Molecule; Illicit; Approved
Other Brand Names containing Quazepam: Cetrane; Doral; Dormalin; Oniria; Prosedar; Quazium; Selepam;
Absorption: Bioavailability is 29-35% following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic.
Half Life: 39 hours
Dosage Forms of Dormalin: Tablet Oral
Chemical IUPAC Name: 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione
Chemical Formula: C17H11ClF4N2S
Quazepam on Wikipedia: https://en.wikipedia.org/wiki/Quazepam
Organisms Affected: Humans and other mammals