Euvitol - General Information
Euvitol (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Reactivan is still rarely used for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases. [Wikipedia]
Pharmacology of Euvitol
Euvitol increases drive and mental alertness and an elevation of mood and a general feeling of well-being. It is a central nervous system stimulant, which increases locomotor activity.
Euvitol for patients
Should not be used in patients with heart disease, angina, glaucoma, thyrotoxicosis or in patients being treated with monoamine oxidase inhibitors.
Additional information about Euvitol
Euvitol Indication: For the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
Mechanism Of Action: Euvitol acts as an indirect dopamine agonist. It releases dopamine by a similar mechanism to amphetamines, but is 10x less potent than dexamphetamine at producing this effect. The main mechanism of action is instead inhibition of dopamine reuptake, more similar to that of methylphenidate. Also unlike amphetamines, fencamfamine does not inhibit the action of monoamine oxidase enzymes and so is somewhat safer. Some experiments also suggest a role for opioid receptors in the activity of fencamfamine, as low doses can cause paradoxical sedation, and some effects of the drug are blocked by naloxone.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Fencamfamine
Synonyms: Fencamfamin; Fencamfamin hydrochloride; Fencamfamine [inn-french]; Fencamfamine hydrochloride; Fencamfaminum [inn-latin]; Fencanfamina [inn-spanish]; Fencamfamina [dcit]; 2-Ethylamino-3-phenylnorcamphane hydrochloride; 2-Ethylamino-3-phenyl-norcamphane hydrochloride; 2-Aethylamino-3-phenyl-nor-camphan
Drug Category: Antipsychotic Agents; Central Nervous System Stimulants
Drug Type: Small Molecule; Illicit; Approved; Withdrawn
Absorption: Not Available
Toxicity (Overdose): Overdosage is characterised by nausea, agitation and restlessness, dryness of the mouth, dizziness and tremor. In gross overdosage the above symptoms may also be associated with dyspnoea, tachycardia, disorientation and convulsions.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Euvitol: Tablet Oral
Chemical IUPAC Name: N-ethyl-6-phenylbicyclo[2.2.1]heptan-5-amine
Chemical Formula: C15H21N
Fencamfamine on Wikipedia: https://en.wikipedia.org/wiki/Fencamfamine
Organisms Affected: Humans and other mammals