Factor S - General Information
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. [PubChem]
Pharmacology of Factor S
Factor S is a water-soluble B-complex vitamin which is composed of an ureido ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Factor S is used in cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Kreb cycle, which is the process in which energy is released from food. Factor S not only assists in various metabolic chemical conversions, but also helps with the transfer of carbon dioxide. Factor S is also helpful in maintaining a steady blood sugar level. Factor S is often recommended for strengthening hair and nails. Consequenty, it is found in many cosmetic and health products for the hair and skin. Factor S deficiency is a rare nutritional disorder caused by a deficiency of biotin. Initial symptoms of biotin deficiency include: Dry skin, Seborrheic dermatitis, Fungal infections, rashes including erythematous periorofacial macular rash, fine and brittle hair, and hair loss or total alopecia. If left untreated, neurological symptoms can develop, including mild depression, which may progress to profound lassitude and, eventually, to somnolence; changes in mental status, generalized muscular pains (myalgias), hyperesthesias and paresthesias. The treatment for biotin deficiency is to simply start taking some biotin supplements. A lack of biotin in infants will lead to a condition called seborrheic dermatitis or "cradle cap". Factor S deficiencies are extremely rare in adults but if it does occur, it will lead to anemia, depression, hair loss, high blood sugar levels, muscle pain, nausea, loss of appetite and inflamed mucous membranes.
Additional information about Factor S
Factor S Indication: For nutritional supplementation, also for treating dietary shortage or imbalance.
Mechanism Of Action: Factor S is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, including gluconeogenesis, lipogenesis, fatty acid biosynthesis, propionate metabolism, and catabolism of branched-chain amino acids.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Biotin
Synonyms: (+)-Biotin; (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid; cis-(+)-Tetrahydro-2-oxothieno[3,4]imidazoline-4-valeric acid; Vitamin H; Vitamin B7; D(+)-Biotin; D-Biotin; Coenzyme R
Drug Category: Dietary supplement; Micronutrient; Vitamins (Vitamin B Complex)
Drug Type: Small Molecule; Nutraceutical; Approved
Absorption: Systemic - approximately 50%
Toxicity (Overdose): Prolonged skin contact may cause irritation.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Factor S: Powder, for solution Oral
Chemical IUPAC Name: 5-[(3aR,6S,6aS)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-6-yl]pentanoic acid
Chemical Formula: C10H16N2O3S
Biotin on Wikipedia: https://en.wikipedia.org/wiki/Biotin
Organisms Affected: Humans and other mammals