Kefglycin - General Information

A cephalorsporin antibiotic. [PubChem]


Pharmacology of Kefglycin

Kefglycin is an antibiotic related to cephalosporin but no longer in common use. It is an orally absorbed derivative of cephalosporin C.


Additional information about Kefglycin

Kefglycin Indication: For treatment of severe infections caused by susceptible bacteria.
Mechanism Of Action: The bactericidal activity of cephaloglycin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs).
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Cephaloglycin
Synonyms: Not Available
Drug Category: Anti-Bacterial Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Cephaloglycin: CEG; Cefaloglicina [INN-Spanish]; Cefaloglycin; Cefaloglycine [INN-French]; Cefaloglycinum [INN-Latin]; Cephaloglycin anhydrous; Cephaloglycine; Cephaoglycin acid; D-Cephaloglycine; Kafocin; Kefglycin;
Absorption: Well absorbed following oral administration.
Toxicity (Overdose): Adverse effects following overdosage include nausea, vomiting, epigastric distress, diarrhea, and convulsions.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Kefglycin: Not Available
Chemical IUPAC Name: (6R,7R)-3-(acetyloxymethyl)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Chemical Formula: C18H19N3O6S
Cephaloglycin on Wikipedia:
Organisms Affected: Enteric bacteria and other eubacteria