Medrifar - General Information
Medrifar is a corticosteroid used in ophthalmology. [Wikipedia]
Pharmacology of Medrifar
Medrifar is a topical anti-inflammatory corticoidsteroids for ophthalmic use. In patients with increased intraocular pressure and in those susceptible to a rise in intraocular pressure, there is less effect on pressure with medrysone than with dexamethasone or betamethasone. Corticoidsteroids inhibit the edema, fibrin deposition, capillary dilation, and phagocytic migration of the acute inflammatory response, as well as capillary proliferation, deposition of collagen, and scar formation.
Medrifar for patients
No Informatuion Provided.
HMS® (medrysone) is contraindicated in the following conditions:
Acute superficial herpes simplex
Viral diseases of the conjunctiva and cornea
Fungal diseases of the eye
Hypersensitivity to any of the components of the drug
Additional information about Medrifar
Medrifar Indication: For the treatment of allergic conjunctivitis, vernal conjunctivitis, episcleritis, and epinephrine sensitivity.
Mechanism Of Action: There is no generally accepted explanation for the mechanism of action of ocular corticosteroids. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Medrysone
Drug Category: Topical anti-inflammatory Agent
Drug Type: Small Molecule; Approved
Other Brand Names containing Medrysone: HMS Liquifilm; Medrifar; Medritonic; Medrocort; Visudrisone; HMS;
Absorption: Rapidly absorbed following oral administration.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Medrifar: Solution / drops Ophthalmic
Chemical IUPAC Name: (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Chemical Formula: C22H32O3
Medrysone on Wikipedia: https://en.wikipedia.org/wiki/Medrysone
Organisms Affected: Humans and other mammals