Natil - General Information

A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Natil is not approved for use in the U.S. or Canada, but is approved in various European countries.


Pharmacology of Natil

Natil is in a class of drugs called vasodilators. Natil relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily.


Additional information about Natil

Natil Indication: Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
Mechanism Of Action: Natil produces peripheral vasodilation by a direct effect on vascular smooth muscle.
Drug Interactions: Not Available
Food Interactions: Take with food to reduce irritation.
Generic Name: Cyclandelate
Synonyms: Cyclandelic acid; Ciclandelato [inn-spanish]; Cyclandelatum [inn-latin]; 3,5,5-Trimethylcyclohexyl mandelate; 3,5,5-Trimethylcyclohexyl amygdalate; 3,3,5-Trimethylcyclohexyl mandelate
Drug Category: Vasodilator Agents
Drug Type: Small Molecule; Approved

Other Brand Names containing Cyclandelate: Arto-espasmol; Capilan; Ciclospasmol; Clandilon; Cyclergine; Cyclobral; Cyclolyt; Cyclomandol; Cyclospasmol; Dilatan; Natil; Novodil; Perebral; Saiclate; Sancyclan; Sepyron; Spasmione; Spasmocyclon; Spasmocyclone; Vasodyl;
Absorption: Well absorbed following oral administration.
Toxicity (Overdose): Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig]
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Natil: Tablet Oral
Chemical IUPAC Name: (3,3,5-trimethylcyclohexyl) 2-hydroxy-2-phenylacetate
Chemical Formula: C17H24O3
Cyclandelate on Wikipedia: Not Available
Organisms Affected: Humans and other mammals