Pacinone - General Information

Pacinone is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a trifluoromethyl derivative of nordazepam. While its structure may be similar to chlordiazepoxide and diazepam, it has both less toxicity and less tendency to cause paradoxical hostility and aggression than either of them. [Wikipedia]


Pharmacology of Pacinone

Not Available


Additional information about Pacinone

Pacinone Indication: Used to relieve anxiety, nervousness, and tension associated with anxiety disorders.
Mechanism Of Action: Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Halazepam
Synonyms: Halazepamum [INN-Latin]
Drug Category: Anti-anxiety Agents; Sedative; Muscle Relaxants; Benzodiazepines
Drug Type: Small Molecule; Illicit; Approved

Other Brand Names containing Halazepam: Pacinone; Paxipam;
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Hepatic.
Half Life: Not Available
Dosage Forms of Pacinone: Tablet Oral
Chemical IUPAC Name: 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepin-2-one
Chemical Formula: C17H12ClF3N2O
Halazepam on Wikipedia:
Organisms Affected: Humans and other mammals