Progesic - General Information
3,6-Diaminoacridine. Topical antiseptic used mainly in wound dressings. [PubChem]
Pharmacology of Progesic
Progesic is an acriflavine derivative which is a disinfectant bacteriostatic against many gram-positive bacteria. Progesic is toxic and carcinogenic in mammals and so it is used only as a surface disinfectant or for treating superficial wounds.
Additional information about Progesic
Progesic Indication: Topical antiseptic used mainly in wound dressings.
Mechanism Of Action: Progesic acts by interchelating DNA (intercalation), thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands. This prevents bacterial reproduction.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Proflavine
Synonyms: Not Available
Drug Category: Anti-Infectives, local
Drug Type: Small Molecule; Approved
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Progesic: Not Available
Chemical IUPAC Name: acridine-3,6-diamine
Chemical Formula: C13H11N3
Proflavine on Wikipedia: https://en.wikipedia.org/wiki/Proflavine
Organisms Affected: Enteric bacteria and other eubacteria