Rescinpal - General Information
Rescinpal is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. [Wikipedia]
Pharmacology of Rescinpal
Used to treat hypertension. Rescinpal inhibits angiotensin-converting enzyme. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex.
Additional information about Rescinpal
Rescinpal Indication: For the treatment of hypertension.
Mechanism Of Action: Binds to and inhibits the angiotensin converting enzyme. Rescinpal competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blood pressure and stimulation of baroreceptor reflex mechanisms, which leads to decreased vasopressor activity and to decreased aldosterone secretion.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Rescinnamine
Synonyms: Methyl Trimethoxycinnamoylreserpate; Trimethoxycinnamoyl Methyl Reserpate; Recinnamine; Rescinnamin; Reserpinene; Reserpinin; Reserpinine
Drug Category: Antihypertensive Agents
Drug Type: Small Molecule; Approved
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Rescinpal: Not Available
Chemical IUPAC Name: Not Available
Chemical Formula: C35H42N2O9
Rescinnamine on Wikipedia: https://en.wikipedia.org/wiki/Rescinnamine
Organisms Affected: Humans and other mammals